Metadata Crosswalk for a Museum Collection in a Thematic Digital Library

The Biblioteca Digital de Arte (BDArt) Digital Library hosted by the Thematic Repository at the University of Porto (Repositório Temático da U.Porto) aggregates documents from the library and the archive collections belonging to the Fine Arts School of the University of Porto (Faculdade de Belas Artes da U.Porto). This school has a museum collection containing a significant set of world-class objects managed with distinct processes and tools from those currently used in libraries and archives elsewhere. Interoperability between the collections of the archive, the library, and the museum is necessary because many works allocated to different collections are closely related and can only be seen as a whole by cross-collection search functionalities. The goal of this work, the first of its kind to be developed at the University of Porto (U. Porto), is to integrate the museum collection with archives and library collections in the repository and to use an open-source technology (DSpace). Our experiment involved the selection of appropriate representations of the objects and the definition of a metadata crosswalk between the original metadata standards and qualified Dublin Core. As a result, we created the BDA Museum Collection as a BDArt subcommunity using an XML export procedure that we expect to be helpful in future developments of other museum collections in the Thematic Repository at U.Port

Academic achievement associated with motor performance and sex in different subcultures

Introduction: School and motor performances demonstrates achievements of children throughout childhood. Gender and the child's developmental context interfere with the differentiated trends of intensity and direction of school and motor performance.Objective: To analyze the association among school performance, motor performance, and the sex of children of different subculturesMethod: The study included 233 children aged 7 to 10 years, 127 boys (8.2 ± 0.92 years) and 106 girls (8.4 ± 0.85 years), from three different subcultures (semi-arid, mountainous, and coastal weather) of Northeast Brazil. Data were collected from the School Performance Test and the Test of Gross Motor Development-2. Descriptive statistics, comparisons, and multivariate multiple linear regressions were used for analysis.Results: It was found that school delays were prevalent in boys, and motor delays, specifically in object control skills, were prevalent in girls. Motor performance is positively associated with performance in writing, reading, and arithmetic, but this relationship is specific for each subculture.Conclusions: There was an association among school performance, motor performance, and the sex of children in different Northeastern subcultures, evidencing the influence of subcultures and gender on the children’s performance.Introduction: School and motor performances demonstrates achievements of children throughout childhood. Gender and the child's developmental context interfere with the differentiated trends of intensity and direction of school and motor performance.Objective: To analyze the association among school performance, motor performance, and the sex of children of different subculturesMethod: The study included 233 children aged 7 to 10 years, 127 boys (8.2 ± 0.92 years) and 106 girls (8.4 ± 0.85 years), from three different subcultures (semi-arid, mountainous, and coastal weather) of Northeast Brazil. Data were collected from the School Performance Test and the Test of Gross Motor Development-2. Descriptive statistics, comparisons, and multivariate multiple linear regressions were used for analysis.Results: It was found that school delays were prevalent in boys, and motor delays, specifically in object control skills, were prevalent in girls. Motor performance is positively associated with performance in writing, reading, and arithmetic, but this relationship is specific for each subculture.Conclusions: There was an association among school performance, motor performance, and the sex of children in different Northeastern subcultures, evidencing the influence of subcultures and gender on the children’s performance

Motor development in the hospitalized infant and its biological and environmental characteristics

Introduction: Hospitalization is a risk factor for delayed motor development, due to the lack of adequate stimulation; therefore, it is important to assess child development during hospital admission.Methods: In this study, motor development of previously healthy hospitalized infants was assessed and associated with biological and environmental characteristics, including length of hospital stay and physiotherapeutic treatment. The assessment was made before discharge, with questionnaires and a motor assessment scale.Results: The sample of 32 infants aged from zero to 18 months had an average length of hospital stay of 4.94±2.39 days. 50% of infants were girls (n = 16) and mostly belonged to socioeconomic class C (n = 16). Length of hospital stay explained only 3.3% of motor development variation, showing no significant impact. Infants from lower socioeconomic classes were nearly six times more susceptible to motor delays than those belonging to higher classes (p = 0.05). During hospitalization, 25% of the sample (n = 8) was treated with physiotherapy. All these patients were hospitalized for respiratory dysfunction and presented five times less chance of altered motor development when compared to those who did not undergo physiotherapy.Conclusion: These results should be interpreted with caution, since the type of physiotherapy care provided and infant’s degree of motor impairment were unknown. In this study, length of stay and hospital environment were not significant risk factors when analyzed individually, concluding that the greater the exposure and the amount of associated factors, the more susceptible the infant will be to present motor delays.Keywords: Child development; hospitalization; developmental disabilities Introduction: Hospitalization is a risk factor for delayed motor development, due to the lack of adequate stimulation; therefore, it is important to assess child development during hospital admission. Methods: In this study, motor development of previously healthy hospitalized infants was assessed and associated with biological and environmental characteristics, including length of hospital stay and physiotherapeutic treatment. The assessment was made before discharge, with questionnaires and a motor assessment scale. Results: The sample of 32 infants aged from zero to 18 months had an average length of hospital stay of 4.94 ± 2.39 days. 50% of infants were girls (n = 16) and mostly belonged to socioeconomic class C (n = 16). Length of hospital stay explained only 3.3% of motor development variation, showing no significant impact. Infants from lower socioeconomic classes were nearly six times more susceptible to motor delays than those belonging to higher classes (p = 0.05). During hospitalization, 25% of the sample (n = 8) was treated with physiotherapy. All these patients were hospitalized for respiratory dysfunction and presented five times less chance of altered motor development when compared to those who did not undergo physiotherapy. Conclusion: These results should be interpreted with caution, since the type of physiotherapy care provided and infant’s degree of motor impairment were unknown. In this study, length of stay and hospital environment were not significant risk factors when analyzed individually, concluding that the greater the exposure and the amount of associated factors, the more susceptible the infant will be to present motor delays.Keywords: Child development; hospitalization; developmental disabilities 

Robustness of the Process of Nucleoid Exclusion of Protein Aggregates in Escherichia coli

Portuguese Foundation for Science and Technology provided funding to Jose Fonseca under grant number PTDC/BBB-MET/1084/2012. Academy of Finland vertical bar Biotieteiden ja Ympariston Tutkimuksen Toimikunta (Forskningsradet for Biovetenskap och Miljo) provided funding to Andre S. Ribeiro under grant number 257603.UNLABELLED: Escherichia coli segregates protein aggregates to the poles by nucleoid exclusion. Combined with cell divisions, this generates heterogeneous aggregate distributions in subsequent cell generations. We studied the robustness of this process with differing medium richness and antibiotics stress, which affect nucleoid size, using multimodal, time-lapse microscopy of live cells expressing both a fluorescently tagged chaperone (IbpA), which identifies in vivo the location of aggregates, and HupA-mCherry, a fluorescent variant of a nucleoid-associated protein. We find that the relative sizes of the nucleoid's major and minor axes change widely, in a positively correlated fashion, with medium richness and antibiotic stress. The aggregate's distribution along the major cell axis also changes between conditions and in agreement with the nucleoid exclusion phenomenon. Consequently, the fraction of aggregates at the midcell region prior to cell division differs between conditions, which will affect the degree of asymmetries in the partitioning of aggregates between cells of future generations. Finally, from the location of the peak of anisotropy in the aggregate displacement distribution, the nucleoid relative size, and the spatiotemporal aggregate distribution, we find that the exclusion of detectable aggregates from midcell is most pronounced in cells with mid-sized nucleoids, which are most common under optimal conditions. We conclude that the aggregate management mechanisms of E. coli are significantly robust but are not immune to stresses due to the tangible effect that these have on nucleoid size. IMPORTANCE: Escherichia coli segregates protein aggregates to the poles by nucleoid exclusion. From live single-cell microscopy studies of the robustness of this process to various stresses known to affect nucleoid size, we find that nucleoid size and aggregate preferential locations change concordantly between conditions. Also, the degree of influence of the nucleoid on aggregate positioning differs between conditions, causing aggregate numbers at midcell to differ in cell division events, which will affect the degree of asymmetries in the partitioning of aggregates between cells of future generations. Finally, we find that aggregate segregation to the cell poles is most pronounced in cells with mid-sized nucleoids. We conclude that the energy-free process of the midcell exclusion of aggregates partially loses effectiveness under stressful conditions.publishersversionpublishe

In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration

The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper describes the in vitro assessment of acyclovir (ACV) into porcine skin from commercial formulations with etermination of drug concentration in different layers of cutaneous tissue to correlate with effective antiviral concentration in order to improve the equivalence decision. Studies were conducted using Franz cells and porcine skin. Selected pharmaceutical creams containing ACV had identical (reference and generic) and different (similar) excipients. A software program was employed for the simulation of antiviral effectiveness in the skin. Regarding ACV skin penetration, the first batch of the generic product showed a significant difference from reference and similar products, while in the second batch all products demonstrated equivalent drug penetration in the skin. Simulation studies suggest that formulations analysed exhibit a pharmacological effect even when in contact with Herpes simplex strains of high IC50 (inhibitory concentration required to reduce viral replication by 50%). According to results, it can be assumed that the in vitro cutaneous permeation/penetration study does not supply sensitivity information regarding small alterations of ACV semisolid formulations due to the variability inherent to the method, although it can be relevant to pharmaceutical equivalence studies in the development of semisolid products

Elaboración de un instrumento para la asistencia de enfermería en la unidad de hemodiálisis

O objetivo deste estudo é relatar a experiência de construção de um instrumento para registro da sistematização da assistência de enfermagem em uma unidade de tratamento dialítico. Para esta construção, utilizou-se o instrumento formulado com base na literatura sobre diagnósticos de enfermagem em pacientes nefropatas. O instrumento de registro foi analisado conforme: diagramação e facilitação do processo. O processo teve como norteador a teoria das Necessidades Humanas Básicas e a taxonomia da North American Nursing Diagnosis Association. O instrumento tem facilitado a implantação do processo de enfermagem na unidade de hemodiálise. Com o seu uso, foi possível o registro organizado e conciso dos dados e uso de informações importantes para o planejamento e avaliação da assistência prestada.This study aimed at developing an instrument to record nursing assistance systematization in a hemodialysis unit. For this development, we used the instrument formulated from literature on nursing diagnosis in nephropathic patients. The record instrument has been analyzed according to: layout and process facilitation. The process relied on the Basic Human Needs Theory and the taxonomy of the North American Nursing Diagnosis Association. The instrument has been facilitating the implementation of the nursing process in the hemodialysis unit. It was possible to record the data in a organized and concise fashion and use key information to plan and evaluate the assistance offered.El objetivo en este estudio fue la construcción de un instrumento para el registro de la sistematización de la atención de enfermeria en una unidad de tratamiento dialítico. Para esta construcción, se utilizó el instrumento formulado con base en la literatura sobre diagnósticos de enfermería en pacientes con nefropatías. El instrumento de registro fue analizado conforme: diagramación y facilitación del proceso. El proceso tuvo como norteador la teoría de las Necesidades Humanas Básicas y la taxonomía de la North American Nursing Diagnosis Association. El instrumento ha facilitado la implantación del proceso de enfermería en la unidad de hemodiálisis. Con su uso, fue posible el registro organizado y conciso de los datos y uso de informaciones importantes para la planificación y evaluación de la asistencia prestada

PUFFIN: A Path-Unifying Feed-Forward Interfaced Network for Vapor Pressure Prediction

Accurately predicting vapor pressure is vital for various industrial and environmental applications. However, obtaining accurate measurements for all compounds of interest is not possible due to the resource and labor intensity of experiments. The demand for resources and labor further multiplies when a temperature-dependent relationship for predicting vapor pressure is desired. In this paper, we propose PUFFIN (Path-Unifying Feed-Forward Interfaced Network), a machine learning framework that combines transfer learning with a new inductive bias node inspired by domain knowledge (the Antoine equation) to improve vapor pressure prediction. By leveraging inductive bias and transfer learning using graph embeddings, PUFFIN outperforms alternative strategies that do not use inductive bias or that use generic descriptors of compounds. The framework's incorporation of domain-specific knowledge to overcome the limitation of poor data availability shows its potential for broader applications in chemical compound analysis, including the prediction of other physicochemical properties. Importantly, our proposed machine learning framework is partially interpretable, because the inductive Antoine node yields network-derived Antoine equation coefficients. It would then be possible to directly incorporate the obtained analytical expression in process design software for better prediction and control of processes occurring in industry and the environment

SELF-PERCEPTION OF COMPETENCE IN CHILDREN FROM SOCIALLY VULNERABLE CONTEXTS, ASSISTED AND UNASSISTED BY SOCIAL SPORTS PROJECTS

ntroduction: practising sport contributes tothe reinforcement of important psychological features such as self-perception of competence, especially when participants are children from socially vulnerable contexts. Objective: to compare the socially vulnerablechildren’s self-perception of competence, assisted and unassisted by social sports projects. Method: a total of 235 children (male and female), aged between seven and tenyears, participated in this comparative study. They were divided into two groups: onegroup was formed by 106 children participating in social sports projects;the other was 129 children who did not participate in socialsports projects. The self-perception of competence was assessed by the Brazilian version of the Self-Perception Profile for Children. We used a three-way ANOVA to assess the possible interaction effect between gender, age and group (children assisted and unassisted) in the different dimensions of perceived competence. Results: The children attending sports projects reported higher overall self-worth (F(1.234)) = 6.132, p = 0.014, η2 = 0.026). It was observed that there was an effect of interaction between the variable age x group (F(1.234)) = 6.673, p = 0.010, η2 = 0.029) on the self-perception of social acceptance. There were no significant effects of group on the other dimensions of self-perception of competence. Conclusion: the children participatingin social sports projects showed more self-perception in terms of social acceptance and self-concept compared tonon-participatory children. This project does not help in other dimensions of self-perception

Cerebral babesiosis outbreak in bovines in the state of Rio Grande do Sul, Brazil

Descreve-se um surto de mortalidade em bovinos por Babesia bovis em abril de 2007, no Município de Picada Café, Rio Grande do Sul. Em um rebanho com 55 novilhas, 28 (50,9%) morreram em cinco dias. A doença iniciou vinte dias após o ingresso dos bovinos na propriedade. Os sinais clínicos incluíam febre, incoordenação, agressividade, anemia, petéquias nas mucosas e morte 1 á 2 dias após. Em 4 animais necropsiados, observaram-se palidez de mucosas, hemorragias múltiplas, esplenomegalia, fígado aumentado e alaranjado, vesícula biliar com parede edemaciada e contendo bile grumosa. Os rins estavam vermelho-escuros e a bexiga continha urina cor de vinho tinto. O encéfalo apresentou cor róseocereja externamente e ao corte, mais marcado no córtex telencefálico, cerebelo e corpo estriado, contrastando com a cor branca da substância branca. Na histologia havia nefrose hemoglobinúrica, necrose hepática paracentral, bilestase canalicular, congestão esplênica, além de congestão com grande quantidade de eritrócitos parasitados por estruturas compatíveis com Babesia bovis na região cortical do encéfalo, também observadas em esfregaços teciduais dessas regiões. A morte de 28 bovinos em 5 dias deveu-se, provavelmente, à falta de imunidade contra o parasito. O tratamento foi realizado com dipropionato de imidocarb nos demais animais, havendo recuperação dos bovinos que apresentavam sinais iniciais leves e não ocorrência de novos casos durante um período de dois meses, quando foram enviados para abate. __________________________________________________________________________________________ ABSTRACTAn outbreak of cattle mortality due to Babesia bovis infection in the county of Picada Café, Rio Grande do Sul, southern Brazil, in April 2007 is described. Twenty eight heifers (50.9%) died, out of a herd of 55 animals, in five days. The disease occurred approximately 20 days after heifers were transferred to this farm. The clinical signs included fever, anemia, aggressiveness, incoordination, petechiae in the mucous membranes and death after 1 to 2 days. The necropsy revealed pale mucous membranes, splenomegaly, enlarged and yellowish liver, congested and edematous gall bladder containing viscous granular bile. The kidneys and urine were dark red. The gray matter of cerebrum and cerebellum had a characteristic cherry-pink color. Hemorrhage was seen in the epicardium and endocardium. The histological findings consisted of hemoglobinuric nephrosis, paracentral hepatic necrosis, bile stasis, spleen congestion. The gray matter of the brain exhibited congestion with erythrocytes parasitized by Babesia bovis, which were also seen in the brain impression smear. The death of 28 heifers in 5 days was attributed to inadequate immunity against the parasite. The application of imidocarb dipropionate in animals presenting the initial stage of the disease and in all other animals of the herd was adopted as preventive treatment and no new cases of the disease happened in the next two months, when they were sent to slaughter